Abcam, Anti-RAB35 antibody [EPR24487-21]

Product details
Patented technology Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on recombinant antibodies.

Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
RAB35 is necessary for maintaining endosomal sorting and recycling by facilitating the formation of tubular recycling compartments. It functions as part of a complex with other molecules like the exocyst complex which is needed for exocytosis. Through these interactions RAB35 ensures the proper distribution of proteins and lipids at the plasma membrane supporting cellular activities such as cell migration and synaptic function in neurons.
Pathways
RAB35 has significant roles in both the endocytic and exocytic pathways operating alongside proteins such as ARF6 and EPIST. In the endocytic pathway RAB35 is involved in the recycling of endosomes ensuring that receptors and other proteins get recycled back to the cell surface. In the exocytic pathway it aids the exocyst complex which is important for vesicle tethering and fusion at the plasma membrane a process vital for cellular secretion and communication.