BD, 339205, Anti-HLA-DR PerCP-Cy™5.5 L243
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Catalog Number: 339205
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| Verified Reactivity | Human |
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| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA) |
| Preparation | The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. |
| Concentration | Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.) |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Application | FC - Quality tested |
| Recommended Usage | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood. |
| Excitation Laser | Red Laser (633 nm) |
| Product Citations | Maas RJ, et al. 2020. Oncoimmunology. 9:1843247. PubMed Shemesh A, et al. 2022. J Exp Med. 219:. PubMed |
| RRID |
| AB_2565238 (BioLegend Cat. No. 339205) AB_2565239 (BioLegend Cat. No. 339206) |
| Structure | Type I transmembrane protein, Siglec family member, 75 kD |
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| Distribution | NK cells, monocytes |
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| Function | Inhibitory receptor of NK cells |
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| Ligand/Receptor | Sialylated glycans (with α2,8 disialyl and α2,6 sialyl residues) |
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| Cell Type | Monocytes, NK cells |
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| Biology Area | Immunology |
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| Molecular Family | CD Molecules, Siglec Molecules |
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| Antigen References | Avril T, et al. 2006. Infection and Immunity 74:4133 Avril T, et al. 2004. J. Immunol. 173:6841 Yamaji T, et al. 2005. Glycobiology 15:667 |
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| Gene ID | 27036 |
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| UniProt | View information about CD328 on UniProt.org |
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| Clone | 6-434 |
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| Regulatory Status | RUO |
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| Workshop | VIII 80652 |
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| Other Names | Siglec7 (Sialic-binding Ig like lectin 7), p75, AIRM1 |
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| Isotype | Mouse IgG1, κ |
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