BD, 340507, FITC Mouse Anti-Human PAC-1 PAC-1 (also known as PAC1)
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Catalog Number: 340507
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| Verified Reactivity | Human |
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| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA) |
| Preparation | The antibody was purified by affinity chromatography, and conjugated with PerCP/Cyanine5.5 under optimal conditions. |
| Concentration | Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.) |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Application | ICFC - Quality tested |
| Recommended Usage | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm. |
| Excitation Laser | Blue Laser (488 nm) |
| Application Notes |
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| Clone 1412 can be used to stain CD20 after the cells have been treated with BioLegend's True-Phos™ Perm Buffer making it ideal for signaling pathway research and simultaneous detection of intracellular targets. |
| RRID | AB_2144523 (BioLegend Cat. No. 340508) |
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| Structure | Four transmembrane protein (TM4SF), heavily phosphorylated after activation, 33-37 kD |
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| Distribution | B cell, T cell subsets |
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| Function | B cell activation |
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| Ligand/Receptor | Src family tyrosine kinases, MHC class I, II, CD53, CD81, CD82 |
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| Cell Type | B cells, T cells |
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| Biology Area | Costimulatory Molecules, Immunology |
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| Molecular Family | CD Molecules |
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| Antigen References | 1. Hultin L, et al. 1993. Cytometry 14:196. 2. Tedder T, et al. 1994. Immunol. Today 15:450. |
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| Gene ID | 931 |
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| UniProt | View information about CD20 on UniProt.org |
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| Clone | 1412 |
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| Regulatory Status | RUO |
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| Other Names | B1, Bp35 |
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| Isotype | Mouse IgG2a, κ |
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