Description
Recombinant human Interleukin-12 (IL-12) produced in CHO cells is a ~75 kDa glycoprotein comprised of disulfide-linked 35kDa (p35) and 40kDa (p40) subunits. IL-12 is produced by activated B lymphocytes and macrophages. The properties of IL-12 include the stimulation of growth of activated T lymphocytes, and actions in the development of Th1 CD4 +ve cells and CD8 +ve cytotoxic T cells. IL-12 also promotes activity and division of NK cells and promotes formation of TH1 cells producing &gamma-interferon.
Storage Information
Prior to reconstitution store at -20°C. Following reconstitution store at -20°C.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
