Biolegend, 367752, PE/Fire™ 744 anti-human KLRG1 (MAFA) Antibody
100tests
Catalog Number: 367752
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| Verified Reactivity | Human |
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| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Immunogen | Human KLRG1-transfected cells |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA) |
| Preparation | The antibody was purified by affinity chromatography and conjugated with PE/Fire™ 744 under optimal conditions. |
| Concentration | Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.) |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Application | FC - Quality tested |
| Recommended Usage | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. True-Stain Monocyte Blocker™ (Cat. No. 426102) is recommended to minimize non-specific staining of PE/Fire™ 744 on monocytes and macrophages. * PE/Fire™ 744 has a maximum excitation of 565 nm and a maximum emission of 744 nm. |
| Excitation Laser | Blue Laser (488 nm)Green Laser (532 nm)/Yellow-Green Laser (561 nm) |
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| RRID | AB_3097454 (BioLegend Cat. No. 367751) AB_3097454 (BioLegend Cat. No. 367752) |
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| Structure | Type II membrane glycoprotein, one C-type lectin domain, one ITIM, 30 kD. |
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| Distribution | Subsets of NK, effector and memory T cells. |
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| Function | Inhibits cell activation and proliferation, marker of T cell senescence. |
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| Interaction | AKT |
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| Ligand/Receptor | E-, N-, and R- cadherins |
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| Cell Type | NK cells, T cells |
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| Biology Area | Immunology, Innate Immunity |
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| Antigen References | 1. Shi L, et al. 2014. J. Immunol. 192:649. |
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| Gene ID | 10219 |
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| UniProt | View information about KLRG1 on UniProt.org |
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| Clone | SA231A2 |
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| Regulatory Status | RUO |
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| Other Names | CLEC15A, MAFA-L, MAFA-2F1, MAFA-LIKE, 2F1 |
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| Isotype | Mouse IgG2a, κ |
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