Description
Description
Hydrophilic filter with low protein adsorption.
Features
Double-layer design
Reliable retention of bacteria and particles
Extensive chemical compatibility
Low leachables
Low protein adsorption
Applications
Buffer filtration
Pre-column/ultra-filtration protection
Quality Standards
ISO 9001: 2015 Quality Management System
Manufactured for use in conformance with cGMP
COA/COQ provided with shipment
How to use a syringe filter?
Choose the right type of membrane material based on the properties of your sample. Be careful of the chemical compatibility to avoid extractables and leachables. Read this article about How to choose a syringe filter.
1. Load the sample into the syringe.
2. Attach the filter to the luer-lock of the syringe with a twisting motion. Make sure it is securely attached.
3. Filter the sample. Hold the syringe and filter vertically, and gently press the plunger to push the sample through the filter. Take care not to apply too much force or you may damage the filter.
4. Discard the used filter and repeat for the next sample.
Specifications

General

DiameterV25 with Luer Vent (3.1 cm²)
ConnectorsInlet: Female Luer Lock + Outlet: Male Luer Slip
SterilityNon-sterile (Autoclavable)

Physical Properties

Filter FormatBricap™ Syringe Filter
ScaleProcess Development, for Filterability Test
Filtration Areaφ13 mm (0.72 cm²) φ25 mm (3.4 cm²) φ33 mm (4.5 cm²) V25 with Luer Vent (3.1 cm²)
Pore Size0.65 μm (final-filter)
Pre-filter1.0 μm
Bubble Point≥0.2 MPa at 20 °C, water wetted, air

Materials

Membrane MaterialPolyethersulfone (PES)
Housing MaterialPolypropylene (PP)

Regulatory Compliance

ComplianceUSP <788> Particulate Matter USP <87> Cytotoxicity USP <88> Biological Reactivity FDA Indirect Food Additives, 21 CFR 177-182 ADCF Materials
Bacterial Retention10⁷ cfu/cm² Brevundimonas diminuta (ATCC 19146) according to ASTM F838
Bacterial EndotoxinEndotoxin Limit of WFI System<0.25 EU/mL with the Limulus Amebocyte Lysate (LAL), USP <85>
Non-Fiber ReleasingThe products meet the criteria as defined in 21 CFR 210.3(b)(6)

Sterility

Sterilization MethodNon-sterile - Autoclavable Pre-sterilized - Gamma irradiation at 25 kGy

Package

Pack SizePack of 100
PackagingIndividually blister packed