Description
Product Usage Information
Western Blotting: 1:1000
Storage
Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at -20°C. Do not aliquot the antibody.
Protocol
Available protocols: Western Blotting
Specificity / Sensitivity
C/EBP delta Antibody detects endogenous levels of total C/EBPδ protein.
Species Reactivity: Mouse
Source / Purification
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the sequence of mouse C/EBPδ. Antibodies are purified by protein A and peptide affinity chromatography.
Background
CCAAT/enhancer-binding proteins (C/EBPs) are a family of transcription factors critical for cellular proliferation, differentiation, metabolism, inflammatory response and many other biological events (1,2). Six members of the family have been identified (C/EBPα, β, δ, γ, ε and ζ) and have been shown to distribute in a variety of tissues (1,2). C/EBPδ is highly expressed in adipose tissue, lung and intestine (2). C/EBPs play an important role in positively regulating adipogenesis (2,3) and C/EBPδ mRNA levels are enhanced during this process (3). C/EBPδ is also expressed in the mammalian nervous system (2) and has been shown to play an important role in long-term memory (4).
Alternate Names
C/EBP delta; C/EBP-delta; CCAAT enhancer binding protein delta; CCAAT/enhancer binding protein (C/EBP), delta; CCAAT/enhancer-binding protein delta; CEBPD; CELF; CRP3; NF-IL6-beta; Nuclear factor NF-IL6-beta
