Description
Product Usage Information
Immunohistochemistry (Paraffin): 1:50 - 1:200
Flow Cytometry (Fixed/Permeabilized): 1:50
Storage
Supplied in PBS (pH 7.2), less than 0.1% sodium azide and 2 mg/ml BSA. Store at 4°C. Do not aliquot the antibody. Protect from light. Do not freeze.
Protocol
Available protocols: Immunohistochemistry (Paraffin), Flow Cytometry (Fixed/Permeabilized)
Specificity / Sensitivity
CD68 (D4B9C) Rabbit Monoclonal Antibody (Alexa Fluor
Species Reactivity: Human, Monkey
Source / Purification
Monoclonal antibody is produced by immunizing animals with recombinant human CD68 protein.
Background
CD68 (macrosialin) is a heavily glycosylated transmembrane protein that is expressed by and commonly used as a marker for monocytes and macrophages (1,2). It is found on the plasma membrane, as well as endosomal and lysosomal membranes (1-3). It is proposed to bind OxLDL and has been observed as a homodimer (3,4).
Alternate Names
CD68; CD68 antigen; CD68 molecule; DKFZp686M18236; Gp110; LAMP4; macrophage antigen CD68; Macrosialin; SCARD1; scavenger receptor class D, member 1
