Description
Product Usage Information
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Storage
Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.
Protocol
Available protocols: Western Blotting, Immunoprecipitation
Specificity / Sensitivity
EXOC7 (E4W6R) Rabbit Monoclonal Antibody recognizes endogenous levels of total EXOC7 protein. This antibody is expected to detect all isoforms of EXOC7. By western blot, this antibody detects a band of approximately 140 kDa of unknown origin in MCF7 cells.
Species Reactivity: Human, Mouse, Rat
Source / Purification
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Arg72 of human EXOC7 protein.
Background
EXOC7/Exo70 is a component of the exocyst complex, which regulates the docking of exocytic vesicles to the plasma membrane and the release of cargo, including neurotransmitters, hormones, and membrane proteins (1). EXOC7 plays a role in cell motility, migration, and invasion, and is an independent prognostic factor in colon cancer (2).
Alternate Names
2-5-3p; BLOM4; DKFZp686J04253; EX070; EXO70; Exo70p; EXOC1; EXOC7; Exocyst complex component 7; Exocyst complex component Exo70; FLJ40965; FLJ46415; KIAA1067; YJL085W
