Description
Product Usage Information
Western Blotting: 1:1000
Storage
Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.
Protocol
Available protocols: Western Blotting
Specificity / Sensitivity
GPX1 (C8C4) Rabbit Monoclonal Antibody detects endogenous levels of total GPX1 protein.
Species Reactivity: Human
Source / Purification
GPX1 (C8C4) Rabbit mAb is produced by immunizing rabbits with a synthetic peptide corresponding to the sequence of human GPX1.
Background
Glutathione peroxidase 1 (GPX1) is a cytosolic selenoprotein which reduces hydrogen peroxide to water (1). GPX1 is the most abundant and ubiquitous among the five GPX isoforms identified so far (2). It is an important component in the anti-oxidative defense in cells and is associated with a variety of disease conditions, such as colon cancer (3), coronary artery disease (4) and insulin resistance (1).
Alternate Names
Cellular glutathione peroxidase; Glutathione peroxidase 1; GPx-1; GPX1; GPXD; GSHPx-1; GSHPX1; MGC14399; MGC88245; selenoprotein GPX1
