Description
Product Usage Information
Western Blotting: 1:1000
Storage
Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at -20°C. Do not aliquot the antibody.
Protocol
Available protocols: Western Blotting
Specificity / Sensitivity
JAKMIP1 Antibody recognizes endogenous levels of total JAKMIP1 protein.
Species Reactivity: Human, Mouse, Rat
Source / Purification
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human JAKMIP1 protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background
JAKMIP1, or Janus kinase and microtubule interactin protein 1, localizes in mitrotubules and the plasma membrane, which associates with microtubules and plays a role in migration of pyramidal neurons (1). JAKMIP1 participates in the microtubule-dependent transport of GABA-B receptor (2). It is also linked to autistic-spectrum disorders (3,4). JAKMIP1 may participate in the JAK1 pathway (5).
Alternate Names
FLJ31564; GABA-B receptor-binding protein; GABABRBP; Jak and microtubule interacting protein 1; JAKMIP1; JAMIP1; janus kinase and microtubule interacting protein 1; Janus kinase and microtubule-interacting protein 1; JKIP1; Marlin-1; MARLIN1; Multiple alpha-helices and RNA-linker protein 1; multiple coiled-coil GABABR1-binding protein
