Description
Product Usage Information
Western Blotting: 1:1000
Storage
Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody.
Protocol
Available protocols: Western Blotting
Specificity / Sensitivity
Perilipin-3 (F8T8T) Rabbit Monoclonal Antibody recognizes endogenous levels of total perilipin-3 protein. This antibody does not cross-react with perilipin-1, perilipin-2, perilipin-4, or perilipin-5 protein.
Species Reactivity: Human
Source / Purification
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human perilipin-3 protein.
Background
Eukaryotic cells store lipids in lipid droplets. These intracellular lipid storage structures are covered by members of the perilipin family of lipid droplet coat proteins. Perilipins establish an interface between stored lipids and the cytosol, and coordinate lipid storage and utilization (1-3). Research studies suggest that perilipin-3 plays a significant role in the biogenesis of lipid droplets (4). In addition, peroxisome proliferator-activated receptor α (PPARα) promotes also known as transcription, lipid droplet accumulation, and cell proliferation in prostate cancer (5).
Alternate Names
47 kDa mannose 6-phosphate receptor-binding protein; 47 kDa MPR-binding protein; cargo selection protein (mannose 6 phosphate receptor binding protein); Cargo selection protein TIP47; M6PRBP1; mannose-6-phosphate receptor binding protein 1; Mannose-6-phosphate receptor-binding protein 1; MGC11117; MGC2012; MPR-binding protein 47 kDa; perilipin 3; Perilipin-3; Placental protein 17; PLIN3; PP17; tail-interacting protein, 47 kD; testicular tissue protein Li 114; TIP47
