Description
PRP-X500 is a superficially porous polymeric anion exchange column. The methacrylate polymeric coating of the PRP-X500 provides a more hydrophilic surface, preventing hydrophobic interaction sample losses typically seen on other commercially available protein HPLC columns. Recovery of the sample is excellent with PRP-X500, and the support’s limited permeability prevents proteins from entering the pores and unfolding, which causes peak ghosting. The superficially porous properties of the packing material improve mass transfer, shortening the diffusion path of the analyte. This results in shortened run times, improved resolution, and sharp sample bands. Application Examples: Proteins, peptides, and DNA/RNA.
