Description
Product Overview Cryopreserved Human Hepatocytes, Plateable format are tested for high viability and healthy culture duration of at least 5 days in 2D sandwich culture. The general purpose plateable hepatocytes are ideal for DMPK studies, disease modeling, genomics applications, and other applications where high quality plated hepatocytes are required. The general purpose Cryopreserved Human Hepatocytes, Plateable are verified for long-term plating, plating in 96-well format, and for spheroid formation capacity. Please download our recent inventory from the link below and look for our Verified for Long Term TM , Verified for 96-well TM and Verified for Spheroids TM Characteristics to select your optimal batch. Request more info Features*: Confluent monolayer with cobblestone morphology, distinct nuclei, and tight junctions for 5 days or more Inducibility of enzyme activity for CYP3A4, CYP2B6, and CYP1A2 Inducibility of mRNA for CYP3A4, CYP2B6, CYP1A2, and CYP2C8 genes Basal metabolism for 8 CYPs, SULT, UGT, and aldehyde oxidase *Currently, older batches may not have a complete data set of characteristics listed Request More Info
Benefits Large inventory of multiple donors Tested for ability to form spheroids in culture Tested for long-term applications and 96-well compatibility Applications DMPK studies Short term cellular toxicity studies Disease modeling Genomics Xenotransplantation 3D cell culture
Storage and Content 1 x Cryopreserved ampule HUCPG containing >5 million viable cells
