Merck, 880134P, PMA

General description
PMA (polymethacrylate) random copolymer is amphiphilic and consists of hydrophobic and hydrophilic sidechains.
Biochem/physiol Actions
PMA (polymethacrylate) forms nanodiscs spontaneously by fragmentation or solubilization of the lipid bilayers. It is used in designing of nanodisc-forming polymer to mimic the amphiphilic nature of proteins and peptides. PMA N−C4−60−4.7 efficiently solubilised the lipid membrane and forms lipid nanodiscs with 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC). The addition of PMA N−C4−60−4.7 lowered the light scattering intensity of Escherichia coli suspension.
Packaging
20mL clear glass screw cap vial (880134P-500mg)
5mL glass amber screw cap vial (880134P-100mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC