Abcam, ab75813-100µL, Anti-NCAM1 antibody [EP2567Y]

Product details
What is this antibody validated in? Anti-NCAM1 antibody [EP2567Y] (ab75813) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human samples. What is the molecular weight of NCAM1? Anti-NCAM1 [EP2567Y] (ab75813) specifically detects a band for NCAM1 (UniProt: P13591) at a molecular weight of 93kDa. Trusted by the scientific community Anti-NCAM1 [EP2567Y] (ab75813) was first used in a scientific publication in 2012 and has been cited over 50 times in peer-reviewed journals. Reviewed by scientists Anti-NCAM1 [EP2567Y] (ab75813) has over 5 independent reviews from customers. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EP2567Y] also available for your convenience: ab75813, Carrier free - ab214435, Carrier free - ab215981, Alexa Fluor® 488 - ab237455, Alexa Fluor® 647 - ab237456, PE - ab237457, APC - ab303037, HRP - ab303038, Alexa Fluor® 594 - ab303718, Alkaline Phosphatase - ab308689, Alexa Fluor® 555 - ab311923, Alexa Fluor® 568 - ab312394, Alexa Fluor® 750 - ab321697
Species reactivity Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
Patented technology Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on recombinant antibodies.

Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
NCAM1 influences neuronal growth survival and synaptic plasticity. This protein is part of the immunoglobulin superfamily and contributes to dynamic interactions during development. NCAM1 exists on cell membranes assisting in the formation and maintenance of tissue structures. In particular cell adhesion molecule CAL53 interacts with NCAM1 highlighting its involvement in synaptic connections. Additionally NCAM1 impacts cellular migration and differentiation particularly in myogenic processes involving MY31's pathway.
Pathways
The NCAM1 protein participates in the MAPK signaling pathway and the PI3K/AKT pathway both essential in cellular growth and survival. NCAM1 acts alongside ERIC1 aiding in the transduction of signals that regulate cytoskeletal rearrangement. These pathways influence cellular communication and responses to external stimuli further enhancing tissue development and regeneration mechanisms.