Merck, 263M-14, CD63 (NKI/C3) Mouse Monoclonal Antibody
Size:0.1 mL
Available Catalog Numbers
Catalog Number: 263M-14
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Category
Pack Size0.1 mL
Description
General description
This antibody reacts with a 53 kDa protein which forms a part of the family of tetraspan moieties. The antigen was originally designated as a lysosomal membrane protein characterized as an activation dependent platelet surface antigen. In fact the CD63 antigen has a diverse distribution on the surface and in the cytoplasm of many cell types including lymphoid, myeloid, endothelial cells and melanoma. It has been quite useful in identifying malignant melanoma. Mete et al. found it useful in differentiating renal oncocytomas (RO) from eosinophilic renal cell carcinomas (eRCC). In his series of 35 ROs, 94% demonstrated apical and/or polar CD63 positivity. Of his 77 eRCCs, 96% showed diffuse cytoplasmic staining.
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Analysis Note
Other Notes
CD63 Positive Control Slides, Product No. 263S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: [email protected]
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
This antibody reacts with a 53 kDa protein which forms a part of the family of tetraspan moieties. The antigen was originally designated as a lysosomal membrane protein characterized as an activation dependent platelet surface antigen. In fact the CD63 antigen has a diverse distribution on the surface and in the cytoplasm of many cell types including lymphoid, myeloid, endothelial cells and melanoma. It has been quite useful in identifying malignant melanoma. Mete et al. found it useful in differentiating renal oncocytomas (RO) from eosinophilic renal cell carcinomas (eRCC). In his series of 35 ROs, 94% demonstrated apical and/or polar CD63 positivity. Of his 77 eRCCs, 96% showed diffuse cytoplasmic staining.
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Analysis Note
 IVD |  IVD |  IVD |  RUO |
Other Notes
CD63 Positive Control Slides, Product No. 263S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: [email protected]
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
Specifications
General
| NACRES | NA.41 |
|---|---|
| UNSPSC Code | 12352203 |
| biological source | mouse |
| conjugate | unconjugated |
| antibody form | diluted ascites fluid |
| antibody product type | primary antibodies |
| clone | NKI/C3, monoclonal |
| description | For In Vitro Diagnostic Use in Select Regions (See Chart) |
| form | buffered aqueous solution |
| species reactivity | human |
| packaging | vial of 0.1 mL concentrate (263M-14) |
| manufacturer/tradename | Cell Marque® |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 |
| isotype | IgG1κ |
| control | melanoma |
| shipped in | wet ice |
| storage temp. | 2-8°C |
| visualization | cytoplasmic, membranous |
| Quality Level | 100 |
| Gene Information | human ... CD63(967) |
