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Merck, 85605-1G, Spermine tetrahydrochloride

Size:1 g, N, N′-Bis(3-aminopropyl)-1, 4-butanediamine tetrahydrochloride, BioUltra, Molecular Biology, ≥99.5% (AT)
Available Catalog Numbers
85605-1G85605-25G85605-5G
Catalog Number: 85605-1G
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Category
General Purpose Solvents
Pack Size1 g
TagsChemistry & BiochemicalsBiochemicalsHigh-Purity Biochemicals & Reagents
CollectionsMerck Biochemicals Collection: Trusted Lab Reagents & BuffersMerck Cell Culture Supplements & Reagents: Complete Solutions for Research & BioproductionMerck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification
Manufacturer's Pagewww.sigmaaldrich.com/US/en/product/SIGMA/85605
Description
Application
Used to precipitate DNA from low salt aqueous buffers.
Biochem/physiol Actions
Mixed NMDA agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).
Mixed NMDA agonist/antagonist at the polyamine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).
Mixed NMDA agonist/antagonist at the polyamine site. Role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).
Other Notes
Spermine precipitation of DNA.
Specifications

General

UNSPSC Code12352116
NACRESNA.26
PubChem Substance ID57653056
EC Number206-189-8
Beilstein/REAXYS Number3911771
MDL numberMFCD00012914
InChI keyXLDKUDAXZWHPFH-UHFFFAOYSA-N
InChI1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H
SMILES stringCl.Cl.Cl.Cl.NCCCNCCCCNCCCN
gradeMolecular Biology
product lineBioUltra
assay≥99.5% (AT)
formpowder
impuritiesDNases, none detected
pH4.5-7.0 (25 °C, 1 M in H2O)
mp310-311 °C (dec.) (lit.)
solubilityH2O: 1 m at 20 °C, clear, colorless to almost colorless
anion tracessulfate (SO42-): ≤50 mg/kg
cation tracesAl: ≤5 mg/kg
<i>λ</i>1 M in H2O
UV absorptionλ: 260 nm Amax: 0.2
Quality Level300
Merck 85605-1G Spermine tetrahydrochloride | IRIGHT