Description
Application
Sodium taurocholate hydrate was used as an emulsifier in in situ preparation of digestive enzymes.
Biochem/physiol Actions
Taurocholic acid is the main end product of cholesterol catabolism. During enterohepatic circulation, bile taurocholic acid is converted by the microorganisms to taurodeoxycholic acid and deoxycholic acid. These are reabsorbed by the liver via a carrier-mediated process and converted by liver enzymes to taurocholic acid.
Preparation Note
Sodium taurocholate hydrate yields a clear, colorless solution in water at 50 mg/ml.
Other Notes
For the solubilization of unconjugated bilirubin
Specifications

General

UNSPSC Code12161902
NACRESNA.77
PubChem Substance ID57653098
EC Number205-653-7
Beilstein/REAXYS Number3901620
MDL numberMFCD00150819
InChI keyRDAJAQDLEFHVNR-NEMAEHQESA-M
InChI1S/C26H45NO7S.Na.H2O/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29;;/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34);;1H2/q;+1;/p-1/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-;;/m1../s1
SMILES stringO.[Na+].C[C@H](CCC(=O)NCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
biological sourceox bile
descriptionanionic
assay≥97.0% (TLC)
formpowder
optical activity[α]20/D +23±1°, c = 3% in H2O (dry matter)
mol wt537.68 g/mol (anhydrous basis)
impurities≤1% taurine
solubilityH2O: 50 mg/mL, clear
functional groupsulfonic acid
Quality Level200
Merck 86339-1G Sodium taurocholate hydrate | IRIGHT