Merck, A6779-100MG, Adenosine 5′-triphosphate, periodate oxidized sodium salt

General description
Adenosine 5′-triphosphate 2′,3′ dialdehyde is a derivative of dialdehyde.
Application
Adenosine 5′-triphosphate, periodate oxidized sodium salt has been used:
as an antagonist of the purinergic receptor, P2 × 7 to inhibit P2 × 7 pathway
as a nonspecific agonist to assess the activity of P2×7-R by the mobilization of Ca2+
to evaluate the physiological significance of elevated intracellular ATP levels
increased P2rx7 expression for osteoclastogenesis in Flcn-deficient cells

Biochem/physiol Actions
Adenosine 5′-triphosphate 2′,3′ dialdehyde is considered as an inhibitor of P2 × 7 receptor.