Merck, D6500-100MG, 2′-Deoxyadenosine 5′-triphosphate disodium salt

Application
2′-Deoxyadenosine 5′-triphosphate (dATP) is used as a substrate by a variety of polymerases including DNA polymerase(s) and reverse transcriptase(s).
2′-Deoxyadenosine 5′-triphosphate disodium salt has been used:

• for Smac- X-linked inhibitor of apoptosis protein (Smac-XIAP) binding assay.
• as a component of polymerase chain reaction (PCR) using AM-toxin primers.
• to determine the affinity constant (Kd) with the transcription termination factor Rho.
• to determine the activity of poly ADP-ribose polymerase 1 (PAPR-1 ).