RFQ
Menu
Merck

Merck, E1271-1G, N-Ethylmaleimide

Size:1 g, NEM, BioXtra, ≥98% (HPLC)
Available Catalog Numbers
E1271-1GE1271-5G
Catalog Number: E1271-1G
Pricing

Send a RFQ.

View RFQ List
Category
General Purpose Solvents
Pack Size1 g
TagsChemistry & BiochemicalsBiochemicalsHigh-Purity Biochemicals & Reagents
CollectionsMerck Biochemicals Collection: Trusted Lab Reagents & BuffersMerck Cell Culture Supplements & Reagents: Complete Solutions for Research & BioproductionMerck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification
Manufacturer's Pagewww.sigmaaldrich.com/US/en/product/SIAL/E1271
Description
Application
Reagent for the covalent modification of cysteine residues in proteins.
Biochem/physiol Actions
Augments currents from native M-channels in sympathetic neurons and acts as an opener for KCNQ2, KCNQ4 and KCNQ5 channels.
Sulfhydryl alkylating agent that inactivates NADP-dependent isocitrate dehydrogenase and many endonucleases.
Specifications

General

UNSPSC Code12352106
NACRESNA.21
PubChem Substance ID24894398
EC Number204-892-4
Beilstein/REAXYS Number112448
MDL numberMFCD00005509
InChI1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3
InChI keyHDFGOPSGAURCEO-UHFFFAOYSA-N
product lineBioXtra
assay≥98% (HPLC)
impurities≤0.001% Phosphorus (P)
ign. residue≤0.1%
bp210 °C (lit.)
Quality Level200
Gene Informationhuman ... SLC6A3(6531), SLC6A4(6532)
SMILES stringCCN1C(=O)C=CC1=O
mp43-46 °C (lit.)
solubility95% ethanol: 50 mg/mL, clear to slightly hazy (colorless to faint yellow)
anion traceschloride (Cl-): ≤0.05%
cation tracesAl: ≤0.0005%
storage temp.2-8°C