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Merck, E18859-10G, Ethyl cyanoformate

Size:10 g, 2-Ethoxy-2-oxoacetonitrile, Cyanocarbonyloxyethane, Cyanoformic acid ethyl ester, Ethoxycarbonyl cyanide, Ethyl carbonocyanidate, ≥95%
Available Catalog Numbers
E18859-10GE18859-50G
Catalog Number: E18859-10G
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Category
Amines
Pack Size10 g
TagsChemistry & BiochemicalsBuilding BlocksOrganic Building Blocks
CollectionsMerck / Sigma‑Aldrich Organic & Fluorinated Building BlocksMerck Cell Culture Supplements & Reagents: Complete Solutions for Research & BioproductionMerck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification
Manufacturer's Pagewww.sigmaaldrich.com/US/en/product/ALDRICH/E18859
Description
Application
Ethyl cyanoformate is a general cyanating agent. It can be used in the nucleophilic addition of cyanide to carbonyl compounds, oxidative cyanation of tertiary amines and in the synthesis of β-cyano-substituted acrylates from alkynes.
Ethyl cyanoformate can be used as a cyanide source for the cyanation of:
Activated olefins in the presence of a titanium catalyst.
Carbonyl compounds catalyzed by 4-dimethylaminopyridine (DMAP) to yield corresponding cyanohydrin carbonates under metal-free and solvent-free conditions.
Aldehydes and 2,2,2-trifluoroacetophenone catalyzed by N-heterocyclic carbene (NHC) to yield corresponding cyanohydrins ethyl carbonates.
Specifications

General

UNSPSC Code12352100
NACRESNA.22
PubChem Substance ID24894440
EC Number210-797-9
Beilstein/REAXYS Number635955
MDL numberMFCD00001836
InChI keyMSMGXWFHBSCQFB-UHFFFAOYSA-N
InChI1S/C4H5NO2/c1-2-7-4(6)3-5/h2H2,1H3
SMILES stringCCOC(=O)C#N
assay≥95%
formliquid
Quality Level100
refractive indexn20/D 1.381 (lit.)
bp115-116 °C (lit.)
density1.003 g/mL at 25 °C (lit.)