Merck, E5750-1G, Ergocalciferol
Size:1 g, Calciferol, Ercalciol, Ergosterol irradiated, Irradiated ergosterol, Vitamin D₂, 40, 000, 000 USP units/g
Available Catalog Numbers
Catalog Number: E5750-1G
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Category
Pack Size1 g
Description
General description
Vitamin D₂ or ergocalciferol is available through dietary supplements or plant sources. It is a provitamin, which is fat-soluble.
Application
Ergocalciferol has been used as a component of the diet for rats, to study its bioavailability from ultraviolet-irradiated D2-rich yeast. It has also been used as a standard for identification and quantification of vitamins, as part of a study to determine the nutritional composition of food fishes.
Biochem/physiol Actions
Ergocalciferol (vitamin D₂) and 25-Hydroxycholecalciferol (vitamin D₃) are the two forms of vitamin D, which are activated in vivo by hydroxylation. Vitamin D2 and D3 may be used in a wide range of studies to assess their effects on function such as immune function and calcium homeostasis.
Ergocalciferol is used for antirachitic treatment. Vitamin D has an active role in bone mineralization. Severe deficiency of this vitamin has been associated with osteomalacia and rickets.
Packaging
Sealed ampule.
Preparation Note
1 USP unit = 1 I.U.
Vitamin D₂ or ergocalciferol is available through dietary supplements or plant sources. It is a provitamin, which is fat-soluble.
Application
Ergocalciferol has been used as a component of the diet for rats, to study its bioavailability from ultraviolet-irradiated D2-rich yeast. It has also been used as a standard for identification and quantification of vitamins, as part of a study to determine the nutritional composition of food fishes.
Biochem/physiol Actions
Ergocalciferol (vitamin D₂) and 25-Hydroxycholecalciferol (vitamin D₃) are the two forms of vitamin D, which are activated in vivo by hydroxylation. Vitamin D2 and D3 may be used in a wide range of studies to assess their effects on function such as immune function and calcium homeostasis.
Ergocalciferol is used for antirachitic treatment. Vitamin D has an active role in bone mineralization. Severe deficiency of this vitamin has been associated with osteomalacia and rickets.
Packaging
Sealed ampule.
Preparation Note
1 USP unit = 1 I.U.
Specifications
General
| NACRES | NA.79 |
|---|---|
| PubChem Substance ID | 24894344 |
| eCl@ss | 34058017 |
| UNSPSC Code | 12352205 |
| EC Number | 200-014-9 |
| MDL number | MFCD00166988 |
| Beilstein/REAXYS Number | 1916682 |
| InChI | 1S/C28H44O/c1-19(2)20(3)9-10-22(5)26-15-16-27-23(8-7-17-28(26,27)6)12-13-24-18-25(29)14-11-21(24)4/h9-10,12-13,19-20,22,25-27,29H,4,7-8,11,14-18H2,1-3,5-6H3/b10-9+,23-12+,24-13-/t20-,22+,25-,26+,27-,28+/m0/s1 |
| InChI key | MECHNRXZTMCUDQ-RKHKHRCZSA-N |
| SMILES string | CC(C)[C@@H](C)/C=C/[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CCC/2)([H])C2=C\C=C(C[C@@H](O)CC3)/C3=C |
| biological source | synthetic (organic) |
| assay | ≥97% |
| form | powder |
| specific activity | 40,000,000 USP units/g |
| technique(s) | HPLC: suitable |
| color | white to off-white |
| Gene Information | human ... VDR(7421) |
| Quality Level | 200 |
| mp | 114-118 °C (lit.) |
| storage temp. | 2-8°C |
