Merck, E6530-10MG, Etomidate

Size:10 mg, (R)-1-(α-Methylbenzyl)imidazole-5-carboxylic acid ethyl ester, Amidate, R16659, >98% (HPLC), powder
Available Catalog Numbers
Catalog Number: E6530-10MG
Pricing

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Pack Size10 mg
Manufacturer's Pagewww.sigmaaldrich.com/US/en/product/SIGMA/E6530
Description
General description
Etomidate is an imidazole derivative, which functions as an nonbarbiturate hypnotic agent. It is used in speech and memory test. Etomidate regulates hemodynamic stability by preserving sympathetic outflow and autonomic reflexes. It inhibits adrenal steroidogenesis.
Biochem/physiol Actions
Etomidate is a general anesthetic; potentiates GABAA transmission
Etomidate is a general anesthetic; potentiates GABAA transmission. The possible neuroprotective effect of etomidate against streptozotocin-induced (STZ-induced) hyperglycaemia were investigated in the rat brain and spinal cord. Etomidate treatment demonstrated neuroprotective effect on the neuronal tissue against the diabetic oxidative damage
Features and Benefits
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Specifications

General

NACRESNA.77
PubChem Substance ID24894630
UNSPSC Code12352200
Web Name Suffix Override>98% (HPLC), GABAA potentiator, powder
EC Number251-385-9
MDL numberMFCD00869295
InChI1S/C14H16N2O2/c1-3-18-14(17)13-9-15-10-16(13)11(2)12-7-5-4-6-8-12/h4-11H,3H2,1-2H3/t11-/m1/s1
InChI keyNPUKDXXFDDZOKR-LLVKDONJSA-N
SMILES stringCCOC(=O)c1cncn1[C@H](C)c2ccccc2
assay>98% (HPLC)
formpowder
colorwhite
solubilityDMSO: >10 mg/mL
originatorJohnson & Johnson
storage temp.2-8°C
Quality Level100
Gene Informationhuman ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879)