Description
Application
Ethylenediaminetetraacetic acid has been used:
as a component of peptide dilution buffer for intracellular BH3 (Bcl-2 homology (BH) domain) profiling and validation
as a medium component in the hepatic stellate cell (HSCs) culture
as a component of homogenization buffer for protein extraction from eye tissues
for stopping benzonase reaction in lysis buffer
Biochem/physiol Actions
Ethylenediaminetetraacetic acid (EDTA) is an anticoagulant, majorly used in preventing clotting of blood samples. EDTA may trigger aggregation of platelets resulting in pseudothrombocytopenia. EDTA along with tetracycline imparts serves as root conditioning agent and provides relief in gum infection. EDTA-tetracycline therapy decreases coronary artery calcium levels in atherosclerosis. Calcium Disodium EDTA administration is effective in slowing down the progression of chronic kidney disease.
