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Merck, E6888-1G, Enalapril maleate salt

Size:1 g, (S)-N-[1-(Ethoxycarbonyl)-3-phenylpropyl]-Ala-Pro maleate salt, powder, ≥98.0% (HPLC)
Available Catalog Numbers
E6888-1GE6888-250MGE6888-5G
Catalog Number: E6888-1G
Pricing

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Category
Phosphatase Inhibitors
Pack Size1 g
CollectionsMerck Cell Culture Supplements & Reagents: Complete Solutions for Research & BioproductionMerck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification
Manufacturer's Pagewww.sigmaaldrich.com/US/en/product/SIGMA/E6888
Description
General description
Enalapril is an angiotensin-converting enzyme inhibitor. It is used to treat heart failure and high blood pressure.
Application
Enalapril maleate salt has been used:
to reduce albumin excretion rate (AER) and glomerular lesions
to examine the effects of enalapril pre-treatment on myocardial injury
to investigate its efficacious doses and schedules for mitigation of radiation lung injury

Biochem/physiol Actions
A long-acting angiotensin-converting enzyme inhibitor.
Features and Benefits
This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Specifications

General

UNSPSC Code12352200
PubChem Substance ID24894639
NACRESNA.77
EC Number278-375-7
Web Name Suffix Override≥98.0% (HPLC), ACE inhibitor, powder
InChI1S/C21H30N2O5.C4H4O5/c1-3-28-19(24)14-17(12-11-16-8-5-4-6-9-16)22-15(2)20(25)23-13-7-10-18(23)21(26)27;5-3(6)1-2-4(7)9-8/h4-6,8-9,15,17-18,22H,3,7,10-14H2,1-2H3,(H,26,27);1-2,8H,(H,5,6)/b;2-1-/t15-,17-,18-;/m0./s1
InChI keyUQKQUZOIQFOJOI-KJHLASMFSA-N
SMILES stringC[C@@H](C(N1[C@H](C(O)=O)CCC1)=O)N[C@H](CC(OCC)=O)CCC2=CC=CC=C2.O=C(OO)/C=C\C(O)=O
formpowder
colorwhite to off-white
solubilitymethanol: ≥50 mg/mL, clear, colorless to yellow
originatorMerck & Co., Inc., Kenilworth, NJ, U.S.
Quality Level100
assay≥98.0% (HPLC)
Merck E6888-1G Enalapril maleate salt | IRIGHT