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Merck, SML0804-25MG, (S)-CPP sodium salt

Size:25 mg, (S)-2-Chloro-3-phenylpropanoic acid sodium salt, (aS)-a-chloro-benzenepropanoic acid sodium salt, ≥96% (HPLC)
Available Catalog Numbers
SML0804-25MGSML0804-5MG
Catalog Number: SML0804-25MG
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Category
General Purpose Incubators
Pack Size25 mg
CollectionsMerck Cell Culture Supplements & Reagents: Complete Solutions for Research & BioproductionMerck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification
Manufacturer's Pagewww.sigmaaldrich.com/US/en/product/SIGMA/SML0804
Description
Biochem/physiol Actions
(S)-CPP is an inhibitor of branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, also know as BDK, or keto acid dehydrogenase kinase.
(S)-CPP is an inhibitor of branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, also know as BDK, or keto acid dehydrogenase kinase. BDK is a negative regulator of BCKDC activity. Inhibition of BDK by (S)-CPP (IC₅₀ = 6.3 μM) leads to complex activation, and significant reduction of plasma levels of leucine/isoleucine and valine in wild type mice.
Specifications

General

NACRESNA.77
PubChem Substance ID329825602
UNSPSC Code12352200
MDL numberMFCD28118980
InChI keyHMHPCHNNVOLTFC-QRPNPIFTSA-M
SMILES string[O-]C([C@@H](Cl)CC1=CC=CC=C1)=O.[Na+]
InChI1S/C9H9ClO2.Na/c10-8(9(11)12)6-7-4-2-1-3-5-7;/h1-5,8H,6H2,(H,11,12);/q;+1/p-1/t8-;/m0./s1
assay≥96% (HPLC)
formpowder
colorwhite to beige
solubilityH2O: 20 mg/mL, clear
storage temp.2-8°C
Quality Level100
Merck SML0804-25MG (S)-CPP sodium salt | IRIGHT