Merck, SML3970-10MG, S1RA

Name: S1RA
Brand: Merck
SKU: SML3970-10MG

Size:10 mg, 4-{2-[5-Methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yloxy]ethyl}morpholine, E 52862, E-52862, E52862, MR 309, MR-309, MR309, ≥98% (HPLC)

Available Catalog Numbers

SML3970-10MG SML3970-50MG

Catalog Number: SML3970-10MG

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Category

General Purpose Incubators

Pack Size10 mg

CollectionsMerck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Manufacturer's Pagewww.sigmaaldrich.com/US/en/product/SIGMA/SML3970

Description

Biochem/physiol Actions
Selective, high-affinity sigma-1 receptor antagonist with antinociceptive efficacy in vivo.

S1RA (E-52862) is a selective, high-affinity sigma-1 receptor antagonist (human/guinea pig σ1 Ki = 17/23.5 nM; σ2 Ki = 9.3 μM/rat, >1 μM/guinea pig). S1RA exerts dose-dependent antinociceptive effects in several neuropathic pain models in mice in vivo (16 - 64 mg/kg i.p.).

Specifications

General

UNSPSC Code	12352200
NACRES	NA.77
MDL number	MFCD25976945
form	powder
assay	≥98% (HPLC)
color	, White to light Brown
solubility	DMSO: 2 mg/mL, clear
storage temp.	room temp
Quality Level	100