Merck, U3750-100G, Uridine

General description
Uridine is a uracil nucleoside, specific for RNA sequence. Uridine is present in blood, seminal fluid and cerebrospinal fluid. Uridine is synthesized in living organisms by de novo and salvage pathways.
Application
Uridine has been used:
as a component of hippocampal neuron medium for culture of primary hippocampal neuron cells
in uridine rescue experiments in mouse embryonic fibroblasts and human breast cancer cells
in chase sequencing experiments

Biochem/physiol Actions
Uridine monophosphate is essential for protein glycosylation, polysaccharide biosynthesis and lipid metabolism. Oral administration of uridine is suggested for anisopoikilocytosis and epileptic encephalopathy disorders. Uridine has numerous biological functions like treating dry eye syndrome, regulating nervous system and favors reproduction. High levels of uridine are implicated in insulin resistance.