Merck, U4133-25MG, URB597

Name: URB597
Brand: Merck
SKU: U4133-25MG

Size:25 mg, Cyclohexylcarbamic acid 3´-carbamoyl-biphenyl-3-yl ester, ≥98% (HPLC), powder

Available Catalog Numbers

U4133-25MG U4133-5MG

Catalog Number: U4133-25MG

Pricing

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Category

General Purpose Incubators

Pack Size25 mg

CollectionsMerck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Manufacturer's Pagewww.sigmaaldrich.com/US/en/product/SIGMA/U4133

Description

General description
URB597 binds to active sites of fatty acid amide hydrolases and inhibits their activity. URB597 alters expression of tyrosine hydroxylase and interacts with abnormal-cannabidiol (Abn-CBD) and peroxisome proliferator-activated receptors (PPARs). URB597 elicits antinociception property via cannabinoid receptor by maintaining endocannabinoid anandamide (AEA) levels. URB597 reduces abnormal hyperactivity in neurons and could be for treatment of seizures and improving synaptic plasticity.
Biochem/physiol Actions
Potent, selective fatty acid amide hydrolase (FAAH) inhibitor.
Preparation Note
URB597 is soluble in DMSO at a concentration that is approximately 14 mg/ml.

Specifications

General

UNSPSC Code	12352200
PubChem Substance ID	329827629
NACRES	NA.77
Web Name Suffix Override	≥98% (HPLC), fatty acid amide hydrolase (FAAH) inhibitor, powder
MDL number	MFCD05863934
SMILES string	NC(=O)c1cccc(c1)-c2cccc(OC(=O)NC3CCCCC3)c2
InChI key	ROFVXGGUISEHAM-UHFFFAOYSA-N
InChI	1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)
description	Drug Control: Új pszichoaktív anyag / New psychoactive substance (Hungary), 78/2022. (XII. 28.) BM rendelet.
assay	≥98% (HPLC)
form	powder
drug control	Új pszichoaktív anyag / New psychoactive substance (Hungary), 78/2022. (XII. 28.) BM rendelet
color	white
solubility	DMSO: soluble ~14 mg/mL
storage temp.	2-8°C
Quality Level	100